Are your Genetics effecting your Sleep?
- Claire Wood
- Sep 17, 2024
- 3 min read

How your Gene Variants Affects Your Sleep: What You Need to Know
We all know how important a good night's sleep is for our health, but did you know that your genes can play a big role in how well you sleep? One specific gene, called MTNR1B, is known for affecting both sleep and blood sugar levels. If you have a certain variant of this gene, it can impact the way your body responds to melatonin, the hormone that helps regulate your sleep-wake cycle.
Let’s break down how the MTNR1B gene variant might be affecting your sleep and what you can do about it.
What Is the MTNR1B Gene?
The MTNR1B gene is responsible for producing a receptor in your body that reacts to melatonin. Melatonin is a hormone that your body produces at night to help you feel sleepy and ready for bed. It’s like your body’s natural sleep signal.
How the MTNR1B Gene Variant Affects Sleep
If you have a specific variant of the MTNR1B gene, your body might not handle melatonin the same way as others do. Here's what happens:
Delayed or Disrupted Sleep:
People with the MTNR1B variant may find it harder to fall asleep. That’s because the way their body reacts to melatonin might be slightly off, making it take longer for them to feel sleepy.
Even once asleep, they may not get the same quality of deep, restorative sleep that others do.
Altered Sleep-Wake Cycles:
This gene variant can throw off your circadian rhythm (your internal body clock). You might feel tired at unusual times, or not feel sleepy when it’s bedtime.
- You might also wake up feeling less refreshed, even after a full night of sleep.
Connection Between Sleep and Blood Sugar
Interestingly, the MTNR1B gene doesn’t just affect sleep—it also impacts insulin production, which helps regulate your blood sugar. Here’s how this comes into play:
Melatonin and insulin are linked. When melatonin levels rise at night, insulin levels usually drop. This is natural. But for people with the MTNR1B variant, this drop in insulin can be more significant.
- This can cause higher blood sugar levels at night and may even make it harder for the body to manage blood sugar during the day. This increases the risk of developing type 2 diabetes over time.
What Can You Do About It?
If you suspect that the MTNR1B gene variant is affecting your sleep, there are a few steps you can take to improve your sleep habits and overall health:
Stick to a Sleep Routine: Going to bed and waking up at the same time each day can help regulate your internal clock, even if the gene variant is causing some disruptions.
Limit Screen Time: Blue light from phones, computers, and TVs can interfere with melatonin production. Try turning off devices at least an hour before bed to help your body wind down naturally.
Watch Your Diet: Since this gene also impacts blood sugar, maintaining a balanced diet with fewer sugary or processed foods can support both sleep and metabolism.
Get Enough Natural Light: Exposing yourself to sunlight during the day helps regulate your melatonin production and keeps your sleep-wake cycle in check.
Consider Genetic Testing: If you're experiencing persistent sleep issues, it might be worth getting tested to see if you have the MTNR1B gene variant. This can give you more insights into how your body processes melatonin and insulin.
Final Thoughts
Sleep is essential for your overall well-being, and the MTNR1B gene variant might explain why some people struggle more with their sleep than others. While you can’t change your genes, understanding how they affect your body can help you take the right steps to improve your sleep and health.
By following healthy sleep habits and managing your diet, you can reduce the impact of this gene on your daily life and enjoy better, more restful sleep.
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